Marksman

Twitch

The Plague Rat

A Zaunite plague rat by birth, but a connoisseur of filth by passion, Twitch is not afraid to get his paws dirty. Aiming a chem-powered crossbow at the gilded heart of Piltover, he has vowed to show those in the city above just how filthy they really are.Read the full story on Riot's Universe site

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P
Deadly Venom
Q
Ambush
W
Venom Cask
E
Contaminate
R
Spray and Pray

Twitch

Overview

On patch 16.21, Twitch is rated A tier in the bot lane, winning 51.9% of 6,993 ranked games with a 7.2% pick rate. The most successful build this patch runs Press the Attack with Flash and Barrier and builds The Collector, Infinity Edge, Runaan's Hurricane, and Boots.

Twitch struggles most against Nilah (35.3%), Yasuo (41.2%), and Ziggs (47.2%) and does best against Viktor (64.3%), Lux (58.3%), and Malzahar (57.1%).

Ranked solo/duo · patch 16.21 · 6,993 games · updated Nov 1, 2026 · How we calculate

51.9%

Win rate

7.2%

Pick rate

Games

16.21

Patch

Playing as Twitch

Twitch's Attack Speed is among the highest in the game; try purchasing items with on-hit effects such as Black Cleaver or Wit's End.
Contaminate has a large range; apply as many stacks of Deadly Venom as possible before using it.
You can catch up to an enemy out of attack range with Venom Cask.

Playing against Twitch

Twitch is fragile. Work with teammates to focus on him when you're able to catch him out of Camouflage.
Spell Shields won't block the damage from Deadly Venom, but they will block the effects Twitch can trigger with it.
If you suspect Twitch has left the lane, let your teammates know that Twitch is ''MIA.''

Guides

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Matchups

All Twitch matchups

Strong against

Viktor64.3%28
Lux58.3%24
Malzahar57.1%28
Draven56.7%150
Jhin55.9%614

Weak against

Nilah35.3%51
Yasuo41.2%114
Ziggs47.2%36
Sivir48.4%64
Xayah49.0%151

Abilities

P
Deadly Venom
Twitch's basic attacks infect the target %i:OnHit% On-Hit, dealing true damage each second.
Q
Ambush
Twitch becomes Camouflaged for a short duration and gains Move Speed. When leaving Camouflage, Twitch gains Attack Speed for a short duration. When an enemy champion with Deadly Venom dies, Ambush's cooldown is reset.
Cooldown: 16Cost: 40Range: 20
W
Venom Cask
Twitch hurls a cask of venom that explodes in an area, slowing targets and applying deadly venom to the target.
Cooldown: 13/12/11/10/9Cost: 70Range: 950
E
Contaminate
Twitch wreaks further havoc on poisoned enemies with a blast of his vile diseases.
Cooldown: 12/11/10/9/8Cost: 50/60/70/80/90Range: 1200
R
Spray and Pray
Twitch unleashes the full power of his crossbow, shooting bolts over a great distance that pierce all enemies caught in their path.
Cooldown: 90Cost: 100Range: 1200